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 EPI 252
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Cancer Epidemiology
EPI 252 Winter 2016 (3 units)



Will be taught at UC Berkeley during 2016-2017 academic year.

OBJECTIVES

The course will cover the fundamentals for evaluating epidemiologic evidence for cancer risk factors (study designs, causal inference); assessing the cancer risk attributable to specific risk factors/exposures (attributable risk, meta-analysis); descriptive epidemiology and global burden of cancer (incidence and mortality data, time trends); cancer biology (carcinogenesis, genetics, molecular biology); important preventable or avoidable exposures (chemicals, nutrition, tobacco, occupation, infection, ionizing radiation); and cancer prevention and control.  Emphasis will be on specific preventable exposures for major cancers and methods for assessing opportunites for prevention.

The course is intended to develop skills in the evaluation of risk factors and exposure prevention.  Students will participate in hands-on exercises and critical review of journal articles.  Participation in class discussion is an important part of the course.  Students will prepare a class project and present interim and final presentations of this work.

At the end of the course, students will understand:

  • Major sites of cancer and their epidemiologic characteristics including age, sex, race and geographic distributions, time trends, and major risk factors.
  • Molecular basis of cancer and carcinogenesis.
  • Causal inference in the context of cancer epidemiology.
  • How to assess the cancer risk attributable to modifiable exposures.
  • Methodologic issues associated with specific study designs for assessing relative and attributable risks of specific exposures for specific neoplasms.
  • Major modifiable exposures of etiologic significance, including their possible mechanisms of action, their distributions in the population, and methodologic issues involved in studying them.
PREREQUISITES

Epidemiologic Methods (EPI 203). Exceptions to this prerequisite may be made with the consent of the Course Director, space permitting.

FACULTY

Course Director:

Robert Hiatt, MD, PhD
Phone: 415-514-8113
email: rhiatt@epi.ucsf.edu

Instructor: Catherine Metayer, MD, PhD
Phone: 510-643-1156
email: cmetayer@berkeley.edu

FORMAT

Course content will be delivered through weekly seminars. These will take place on Wednesdays from 9:30 AM-12:30 PM, Jan. 6 to Mar. 9.

All course materials will be posted on the course's online syllabus.

GRADING

Grading will be based on the student's course participation and written assignments (40% of the grade) and written and oral presentations of research project (60% of the grade).

ENROLLMENT

Application

Course fees covered by the Department of Epidemiology and Biostatistics.