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 EPI 207

Epidemiologic Methods II
EPI 207 Winter 2019 (3 units)


Epidemiologic Methods II is designed to extend upon the instruction offered in Epidemiologic Methods (EPI 203). Topics will include advanced coverage of study design, measurement, and overcoming threats to validity. The specific objectives are to instruct students to be able to:

  • Design the most appropriate study for a given research question;
  • Choose or create measurements that will yield the most accurate and precise inference;
  • Detect threats to validity in any research study; and
  • Perform quantitative bias analysis for selection, measurements, and confounding bias.

Epidemiologic Methods (EPI 203), or equivalent, and Biostatistical Methods for Clinical Research I (BIOSTAT 200), or equivalent experience, are required. Experience with the Stata software program is also required.


Course Director:

June Chan, ScD
Phone: 415-415-4923
email: june.chan@ucsf.edu

Teaching Assistant: Monica Ospina Romero, MD
email: monica.ospinaromero@ucsf.edu
Francois Rerolle, MS
email: Francois.Rerolle@ucsf.edu


Each week, new material is introduced via a pre-recorded lecture and required readings. Homework, in the form of a problem set, is assigned each week and is due one week after the lecture at which time it will be discussed with course faculty in small group discussion section.

While lectures are pre-recorded and are to be viewed on the trainee's own time frame, the small groups discussions sections are a critical venue for group learning. Therefore, attendance is highly encouraged. Small group discussion sections will meet on Thursday from 1:15 PM to 3:15 PM, Jan. 10 to Mar. 21.

All course materials and handouts will be posted on the course's online syllabus.


Modern Epidemiology by K. Rothman et al. Lippincott-Raven Publishers. 3rd edition. 2008. UCSF users can access an electronic version of the book at UCSF library.

Causal Inference by M. Hernán, et al. Chapman & Hall/CRC. Forthcoming. A PDF of the book draft is available at the Harvard School of Public Health.

Health Measurement Scales: A Practical Guide to Their Development and Use by D. Streiner, G. Norman, and J. Cairney. Oxford University Press, 5th Edition, 2015.

Explanation in Causal Inference: Methods for Mediation and Interaction by T. VanderWeele. Oxford University Press. 2015.

Epidemiology: An Introduction by K. Rothman, Oxford University Press. 2nd edition, 2012.

Books may be purchased either through the publisher or a variety of commercial venues (e.g., Amazon.com). All textbooks have been placed on the Course Reserves section of the Mission Bay library. Check availability here: http://ucsfcat.library.ucsf.edu/search/?searchtype=r&searcharg=Epi+207


Student grades will be assigned as follows:

  • 9 Homework assignments, each worth 5% (45%)
  • Mid-term quiz (15%)
  • Final Exam (40%)

Students not in full-year TICR Programs who satisfactorily pass all course requirements will, upon request, receive a Certificate of Course Completion.

UCSF Graduate Division Policy on Disabilities


This course is sponsored by the Training in Clinical Research (TICR) Program, and space is limited. Preference is given to UCSF-affiliated personnel. We regret that auditing is not permitted.

To apply for this course, please fill out and submit the application below. Please see our fees page for cost information. The deadline for application is December 21, 2018. Only one application needs to be completed for all courses desired during the quarter.

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