Biostatistical Methods for Clinical Research IV

BIOSTAT 210 Fall 2021 (2 units)
Course Director: David Glidden, PhD
Department of Epidemiology & Biostatistics


This is a fourth course in statistics, covering advanced methods for building and evaluating regression models. The emphasis is on methods which cut across common families of regression models in biostatistics: exposure variable selection, model diagnostics and model comparison. The statistics package Stata will be used throughout the course.


Designing Clinical Research (EPI 202), Biostatistical Methods I (Biostat 200), Biostatistical Methods II (BIOSTAT 208) and III (BIOSTAT 209). Exceptions may be made with the consent of the course director, space permitting.

Course Director:

David Glidden, PhD
email: david.glidden@ucsf.edu

Computer Laboratory Assistant: Kristen Azar, MSN/MPH
email: kristen.azar@ucsf.edu
Safyer Mckenzie-Sampson, MS
email: safyer.mckenzie-sampson@ucsf.edu

Large Group Discussion:
Content: Brief formal review of lecture followed by question and answer discussion. Recorded lecture should be viewed prior to this session
Time: Tuesdays, 10:30 AM to 12:00 PM, beginning September 14

Computer Laboratory:
Content: Course faculty are available to address questions on course assignments
Time: Tuesdays, 3:15 PM to 4:15 PM, September 28, October 11, 26, November 9


Regression Methods in Biostatistics by Vittinghoff et al. Springer Publisher. 2nd Edition. 2012.

Stata Statistical Software (Stata Corporation, College Station, TX) version 14 or higher is acceptable. A six-month student license for Stata/IC is the least expensive option that will be suitable to complete all course assignments, but Stata/SE is recommended for robust future use. The TICR Program has arranged for a sizeable discount for UCSF-affiliated personnel.

Books may be purchased either through the publisher or a variety of commercial venues (e.g., Amazon.com).


Grades will be based on 8 homework assignments.

Students not in full-year TICR Programs who satisfactorily pass all course requirements will, upon request, receive a Certificate of Course Completion.

UCSF Graduate Division Policy on Disabilities


This course is sponsored by the Training in Clinical Research (TICR) Program, and space is limited. Preference is given to UCSF-affiliated personnel. We regret that auditing in the classroom is not permitted, but most of the course materials (with the exception of videotapes, answer keys, examinations, and copyrighted documents) are freely available (without formal enrollment) on the course’s online syllabus. Many students can glean the majority of the course’s content from this free access, but, importantly, formal enrollment also provides access to faculty for questions and individual-level extension of the curriculum, a community of other engaged students for in-person real-time discussion, and personalized correction and feedback on homework and projects.

To enroll in this course, please fill out and submit the application below. Please see our fees page for cost information. The deadline for application is September 3, 2021. Only one application needs to be completed for all courses desired during the quarter.

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