Epidemiologic Methods II

EPI 207 Winter 2022
Course Director: June Chan, ScD
Department of Epidemiology & Biostatistics
Course Co-Director: Rebecca Graff, ScD
Assistant Professor
Department of Epidemiology & Biostatistics


Epidemiologic Methods II is designed to extend upon the instruction offered in Epidemiologic Methods (EPI 203). Topics include advanced coverage of study design, measurement, and overcoming threats to validity. The overarching objective is to help you build skills in the design, conduct, analysis, and interpretation of epidemiologic research.

Specific objectives are for the student to:

  • Understand common study designs used in observational epidemiologic research;
  • Identify sources of bias in observational studies;
  • Understand and practice applying methods to address bias in observational studies;
  • Identify effect modification (interaction) and how to present this in results; and
  • Gain experience in interpreting data and critiquing results from observational studies.

Epidemiologic Methods (EPI 203), or equivalent, and Biostatistical Methods for Clinical Research I (BIOSTAT 200), or equivalent experience, are required. Experience with the Stata software program is also required.

Course Director:

June Chan, ScD
Phone: 415-415-4923
email: June.Chan@ucsf.edu

Course Co-Director:

Rebecca Graff, ScD
Phone: 415-415-4923
email: rebecca.graff@ucsf.edu

Teaching Assistants:

Sarah Goldberg
email: Sarah.Goldberg@ucsf.edu


Carolyn Smith-Hughes, MS
email: Carolyn.Smithhughes@ucsf.edu


Each week, new material is introduced via a live and/or pre¬recorded lecture and required readings. Seven homeworks, in the form of problem sets, will be assigned during the course, and students will have one or two weeks to complete them. Upon submission, homeworks will be discussed with course faculty and teaching assistants in a review session.

Live lectures will be recorded in real-time and made available the same day, after class. Participation is critical for learning, so attendance at live lectures and homework review sections is highly encouraged.

The daily schedule of activities will be posted on the course's online syllabus.


Modern Epidemiology by K. Rothman, S. Greenland, and K. Last. Wolters Kluwer. 3rd edition. 2012. UCSF users can access an electronic version of the book at UCSF library.

Causal Inference by M. Hernán and J. Robins. Chapman & Hall/CRC. Forthcoming.

Books may be purchased either through the publisher or a variety of commercial venues (e.g., Amazon.com). All textbooks have been placed on the Course Reserves section of the Mission Bay library. Check availability here: https://ucsfcat.library.ucsf.edu/search/?searchtype=r&searcharg=Epi+207


Student grades will be assigned as follows:

  • 7 Homework assignments (70%; we drop the lowest score)
  • Final Exam (30%)

Students not in full-year TICR Programs who satisfactorily pass all course requirements will, upon request, receive a Certificate of Course Completion.

UCSF Graduate Division Policy on Disabilities


This course is sponsored by the Training in Clinical Research (TICR) Program, and space is limited. Preference is given to UCSF-affiliated personnel. We regret that auditing in the classroom is not permitted, but most of the course materials (with the exception of videotapes, answer keys, examinations, and copyrighted documents) are freely available (without formal enrollment) on the course’s online syllabus. Many students can glean the majority of the course’s content from this free access, but, importantly, formal enrollment also provides access to faculty for questions and individual-level extension of the curriculum, a community of other engaged students for in-person real-time discussion, and personalized correction and feedback on homework and projects.

To enroll in this course, please fill out and submit the application below. Please see our fees page for cost information. The deadline for application is December 20, 2021. Only one application needs to be completed for all courses desired during the quarter.

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